Benutzer: Gast  Login
Mehr Felder
Einfache Suche
Titel:

Diversification and coevolution of the ghrelin/growth hormone secretagogue receptor system in vertebrates.

Dokumenttyp:
Journal Article; Article
Autor(en):
Tine, Mbaye; Kuhl, Heiner; Teske, Peter R; Tschöp, Matthias H; Jastroch, Martin
Abstract:
The gut hormone ghrelin is involved in numerous metabolic functions, such as the stimulation of growth hormone secretion, gastric motility, and food intake. Ghrelin is modified by ghrelin O-acyltransferase (GOAT) or membrane-bound O-acyltransferase domain-containing 4 (MBOAT4) enabling action through the growth hormone secretagogue receptors (GHS-R). During the course of evolution, initially strong ligand/receptor specificities can be disrupted by genomic changes, potentially modifying physiolog...     »
Zeitschriftentitel:
Ecol Evol
Jahr:
2016
Band / Volume:
6
Heft / Issue:
8
Seitenangaben Beitrag:
2516-35
Volltext / DOI:
doi:10.1002/ece3.2057
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27066235
TUM Einrichtung:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
 BibTeX