Benutzer: Gast  Login
Titel:

Immunohistochemically Characterized Intratumoral Heterogeneity Is a Prognostic Marker in Human Glioblastoma.

Dokumenttyp:
Journal Article
Autor(en):
Liesche-Starnecker, Friederike; Mayer, Karoline; Kofler, Florian; Baur, Sandra; Schmidt-Graf, Friederike; Kempter, Johanna; Prokop, Georg; Pfarr, Nicole; Wei, Wu; Gempt, Jens; Combs, Stephanie E; Zimmer, Claus; Meyer, Bernhard; Wiestler, Benedikt; Schlegel, Jürgen
Abstract:
Tumor heterogeneity is considered to be a hallmark of glioblastoma (GBM). Only more recently, it has become apparent that GBM is not only heterogeneous between patients (intertumoral heterogeneity) but more importantly, also within individual patients (intratumoral heterogeneity). In this study, we focused on assessing intratumoral heterogeneity. For this purpose, the heterogeneity of 38 treatment-naïve GBM was characterized by immunohistochemistry. Perceptible areas were rated for ALDH1A3, EGFR...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2020
Band / Volume:
12
Heft / Issue:
10
Volltext / DOI:
doi:10.3390/cancers12102964
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33066251
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Neurochirurgische Klinik und Poliklinik; Neurologische Klinik und Poliklinik
 BibTeX