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Title:

Enhanced platelet inhibition by clopidogrel and risk of bleeding in patients requiring oral anticoagulation after drug-eluting stent implantation.

Document type:
Journal Article
Author(s):
Goedel, Alexander; Fiedler, Katrin A; Mehilli, Julinda; Bernlochner, Isabell; von Olshausen, Gesa; Mayer, Katharina; Schüpke, Stefanie; Hoppmann, Petra; Sibbing, Dirk; Maeng, Michael; Massberg, Steffen; Schunkert, Heribert; Laugwitz, Karl-Ludwig; Kastrati, Adnan; Sarafoff, Nikolaus
Abstract:
AIMS: Clopidogrel is the P2Y12 inhibitor of choice in patients who undergo PCI and have an indication for oral anticoagulation (OAC). Prediction of the bleeding risk is of major interest in this population. The aim of this analysis was to investigate whether an enhanced platelet inhibition by clopidogrel measured by platelet function testing (PFT) with the Multiplate Analyzer is associated with an increased bleeding risk in patients on triple antithrombotic therapy. METHODS AND RESULTS: This inv...     »
Journal title abbreviation:
EuroIntervention
Year:
2019
Journal volume:
15
Journal issue:
8
Pages contribution:
700-706
Fulltext / DOI:
doi:10.4244/EIJ-D-18-00995
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30834895
Print-ISSN:
1774-024X
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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