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Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Siafis, Spyridon; Deste, Giacomo; Ceraso, Anna; Mussoni, Christian; Vita, Antonio; Hasanagic, Senad; Schneider-Thoma, Johannes; Papazisis, Georgios; Davis, John M; Leucht, Stefan
Title:
Antipsychotic drugs v. barbiturates or benzodiazepines used as active placebos for schizophrenia: a systematic review and meta-analysis.
Abstract:
BACKGROUND: Comparisons of antipsychotics with placebo can be biased by unblinding due to side effects. Therefore, this meta-analysis compared the efficacy of antipsychotics for acute schizophrenia in trials using barbiturates or benzodiazepines as active placebos. METHODS: Randomized controlled trials (RCTs) in acute schizophrenia with at least 3 weeks duration and comparing any antipsychotic with barbiturates or benzodiazepines were eligible. ClinicalTrials.gov, CENTRAL, EMBASE, MEDLINE, PsycI...     »
Journal title abbreviation:
Psychol Med
Year:
2020
Journal volume:
50
Journal issue:
15
Pages contribution:
2622-2633
Fulltext / DOI:
doi:10.1017/S003329171900285X
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31625485
Print-ISSN:
0033-2917
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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