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Title:

Molecular imaging of expression of vascular endothelial growth factor a (VEGF a) in femoral bone grafts transplanted into living mice.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Strachna, Olga; Torrecilla, Daniel; Reumann, Marie K; Serganova, Inna; Kim, Jihye; Gieschler, Simone; Boskey, Adele L; Blasberg, Ronald G; Mayer-Kuckuk, Philipp
Abstract:
The biology of cells transplanted with bone grafts is incompletely understood. Focusing on the early angiogenic response postgrafting, we report a mouse femur graft model in which grafts were derived from mice transgenic for a firefly luciferase (FLuc) bioluminescence reporter gene driven by a promoter for the angiogenic signaling molecule vascular endothelial growth factor (VEGF). Upon transplantation into wild-type (wt) mice, in vivo bioluminescence imaging (BLI) permitted longitudinal visuali...     »
Journal title abbreviation:
Cell Transplant
Year:
2014
Journal volume:
23
Journal issue:
7
Pages contribution:
901-12
Language:
eng
Fulltext / DOI:
doi:10.3727/096368912X667015
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23582187
Print-ISSN:
0963-6897
TUM Institution:
Klinik und Poliklinik für Orthopädie und Sportorthopädie
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