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Title:

Linking Complement C3 and B Cells in Nasal Polyposis.

Document type:
Article; Journal Article
Author(s):
Werner, Ulrike; Künstner, Axel; Drenckhan, Maren; Pries, Ralph; Bruchhage, Karl-Ludwig; Busch, Hauke S; Bachert, Claus; Wollenberg, Barbara
Abstract:
Nasal polyposis often is characterized by a persistent inflammation of the sinonasal mucosa, disease recurrence after medical or surgical intervention, and asthma comorbidity. Dysregulated complement activation may contribute to immunologic alterations and disease. To date, there is only scattered knowledge on the source and regulation of the central complement factors in the pathogenesis of nasal polyps. Here, we aim to study complement signatures, especially the C3-C3aR axis, and focus on cell...     »
Journal title abbreviation:
J Immunol Res
Year:
2020
Journal volume:
2020
Fulltext / DOI:
doi:10.1155/2020/4832189
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32724828
Print-ISSN:
2314-8861
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik
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