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Title:

The Role of miRNA for the Treatment of MGMT Unmethylated Glioblastoma Multiforme.

Document type:
Review; Journal Article; Review
Author(s):
Kirstein, Anna; Schmid, Thomas E; Combs, Stephanie E
Abstract:
Glioblastoma multiforme (GBM) is the most common high-grade intracranial tumor in adults. It is characterized by uncontrolled proliferation, diffuse infiltration due to high invasive and migratory capacities, as well as intense resistance to chemo- and radiotherapy. With a five-year survival of less than 3% and an average survival rate of 12 months after diagnosis, GBM has become a focus of current research to urgently develop new therapeutic approaches in order to prolong survival of GBM patien...     »
Journal title abbreviation:
Cancers (Basel)
Year:
2020
Journal volume:
12
Journal issue:
5
Fulltext / DOI:
doi:10.3390/cancers12051099
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32354046
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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