User: Guest  Login
Less Searchfields
Simple search
Title:

Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes.

Document type:
Article; Journal Article
Author(s):
Popovic, David; Ruef, Anne; Dwyer, Dominic B; Antonucci, Linda A; Eder, Julia; Sanfelici, Rachele; Kambeitz-Ilankovic, Lana; Oztuerk, Omer Faruk; Dong, Mark S; Paul, Riya; Paolini, Marco; Hedderich, Dennis; Haidl, Theresa; Kambeitz, Joseph; Ruhrmann, Stephan; Chisholm, Katharine; Schultze-Lutter, Frauke; Falkai, Peter; Pergola, Giulio; Blasi, Giuseppe; Bertolino, Alessandro; Lencer, Rebekka; Dannlowski, Udo; Upthegrove, Rachel; Salokangas, Raimo K R; Pantelis, Christos; Meisenzahl, Eva; Wood, St...     »
Abstract:
BACKGROUND: Childhood trauma (CT) is a major yet elusive psychiatric risk factor, whose multidimensional conceptualization and heterogeneous effects on brain morphology might demand advanced mathematical modeling. Therefore, we present an unsupervised machine learning approach to characterize the clinical and neuroanatomical complexity of CT in a larger, transdiagnostic context. METHODS: We used a multicenter European cohort of 1076 female and male individuals (discovery: n = 649; replication:...     »
Journal title abbreviation:
Biol Psychiatry
Year:
2020
Journal volume:
88
Journal issue:
11
Pages contribution:
829-842
Fulltext / DOI:
doi:10.1016/j.biopsych.2020.05.020
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32782139
Print-ISSN:
0006-3223
TUM Institution:
1477; 1695; 595; Fachgebiet Neuroradiologie (Prof. Zimmer)
 BibTeX