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Title:

Altered subcortical emotional salience processing differentiates Parkinson's patients with and without psychotic symptoms.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Knolle, F; Garofalo, S; Viviani, R; Justicia, A; Ermakova, A O; Blank, H; Williams, G B; Arrondo, G; Ramachandra, P; Tudor-Sfetea, C; Bunzeck, N; Duezel, E; Robbins, T W; Barker, R A; Murray, G K
Abstract:
OBJECTIVE: Current research does not provide a clear explanation for why some patients with Parkinson's Disease (PD) develop psychotic symptoms. The 'aberrant salience hypothesis' of psychosis has been influential and proposes that dopaminergic dysregulation leads to inappropriate attribution of salience to irrelevant/non-informative stimuli, facilitating the formation of hallucinations and delusions. The aim of this study is to investigate whether non-motivational salience is altered in PD pati...     »
Journal title abbreviation:
Neuroimage Clin
Year:
2020
Journal volume:
27
Fulltext / DOI:
doi:10.1016/j.nicl.2020.102277
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32540629
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer)
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