A compendium answering 150 questions on COVID-19 and SARS-CoV-2.

Riggioni, Carmen; Comberiati, Pasquale; Giovannini, Mattia; Agache, Ioana; Akdis, Mübeccel; Alves-Correia, Magna; Antó, Josep M; Arcolaci, Alessandra; Azkur, Ahmet Kursat; Azkur, Dilek; Beken, Burcin; Boccabella, Cristina; Bousquet, Jean; Breiteneder, Heimo; Carvalho, Daniela; De Las Vecillas, Leticia; Diamant, Zuzana; Eguiluz-Gracia, Ibon; Eiwegger, Thomas; Eyerich, Stefanie; Fokkens, Wytske; Gao, Ya-Dong; Hannachi, Farah; Johnston, Sebastian L; Jutel, Marek; Karavelia, Aspasia; Klimek, Ludger; Moya, Beatriz; Nadeau, Kari C; O'Hehir, Robyn; O'Mahony, Liam; Pfaar, Oliver; Sanak, Marek; Schwarze, Jürgen; Sokolowska, Milena; Torres, María J; van de Veen, Willem; van Zelm, Menno C; Wang, De Yun; Zhang, Luo; Jiménez-Saiz, Rodrigo; Akdis, Cezmi A     «

Riggioni, Carmen; Comberiati, Pasquale; Giovannini, Mattia; Agache, Ioana; Akdis, Mübeccel; Alves-Correia, Magna; Antó, Josep M; Arcolaci, Alessandra; Azkur, Ahmet Kursat; Azkur, Dilek; Beken, Burcin; Boccabella, Cristina; Bousquet, Jean; Breiteneder, Heimo; Carvalho, Daniela; De Las Vecillas, Leticia; Diamant, Zuzana; Eguiluz-Gracia, Ibon; Eiwegger, Thomas; Eyerich, Stefanie; Fokkens, Wytske; Gao, Ya-Dong; Hannachi, Farah; Johnston, Sebastian L; Jutel, Marek; Karavelia, Aspasia; Klimek, Ludger;...     »

In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID-19). This disease, caused by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), has developed into a pandemic. To date, it has resulted in ~9 million confirmed cases and caused almost 500 000 related deaths worldwide. Unequivocally, the COVID-19 pandemic is the gravest health and socioeconomic crisis of our time. In this context, numerous questions have emerged in demand of basic scientific information and evidence-based medical advice on SARS-CoV-2 and COVID-19. Although the majority of the patients show a very mild, self-limiting viral respiratory disease, many clinical manifestations in severe patients are unique to COVID-19, such as severe lymphopenia and eosinopenia, extensive pneumonia, a "cytokine storm" leading to acute respiratory distress syndrome, endothelitis, thromboembolic complications, and multiorgan failure. The epidemiologic features of COVID-19 are distinctive and have changed throughout the pandemic. Vaccine and drug development studies and clinical trials are rapidly growing at an unprecedented speed. However, basic and clinical research on COVID-19-related topics should be based on more coordinated high-quality studies. This paper answers pressing questions, formulated by young clinicians and scientists, on SARS-CoV-2, COVID-19, and allergy, focusing on the following topics: virology, immunology, diagnosis, management of patients with allergic disease and asthma, treatment, clinical trials, drug discovery, vaccine development, and epidemiology. A total of 150 questions were answered by experts in the field providing a comprehensive and practical overview of COVID-19 and allergic disease.      «

In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID-19). This disease, caused by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), has developed into a pandemic. To date, it has resulted in ~9 million confirmed cases and caused almost 500 000 related deaths worldwide. Unequivocally, the COVID-19 pandemic is the gravest health and socioeconomic crisis of our time. In this context, numerous questions have emerged in demand of basic scient...     »