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Title:

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Coakley, Gillian; Volpe, Beatrice; Bouchery, Tiffany; Shah, Kathleen; Butler, Alana; Geldhof, Peter; Hatherill, Mark; Horsnell, William G C; Esser-von Bieren, Julia; Harris, Nicola Laraine
Abstract:
Helminth infection represents a major health problem causing approximately 5 million disability-adjusted life years worldwide. Concerns that repeated anti-helminthic treatment may lead to drug resistance render it important that vaccines are developed but will require increased understanding of the immune-mediated cellular and antibody responses to helminth infection. IL-4 or antibody-activated murine macrophages are known to immobilize parasitic nematode larvae, but few studies have addressed w...     »
Journal title abbreviation:
Parasite Immunol
Year:
2020
Journal volume:
42
Journal issue:
7
Fulltext / DOI:
doi:10.1111/pim.12728
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32394439
Print-ISSN:
0141-9838
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
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