User: Guest  Login
Title:

Reduced Latency in the Metastatic Niche Contributes to the More Aggressive Phenotype of LM8 Compared to Dunn Osteosarcoma Cells.

Document type:
Journal Article
Author(s):
Arlt, Matthias J E; Banke, Ingo J; Bertz, Josefine; Ram Kumar, Ram Mohan; Muff, Roman; Born, Walter; Fuchs, Bruno
Abstract:
Metastasis is the major cause of death of osteosarcoma patients and its diagnosis remains difficult. In preclinical studies, however, forced expression of reporter genes in osteosarcoma cells has remarkably improved the detection of micrometastases and, consequently, the quality of the studies. We recently showed that Dunn cells equipped with a lacZ reporter gene disseminated from subcutaneous primary tumors as frequently as their highly metastatic subline LM8, but only LM8 cells grew to macrome...     »
Journal title abbreviation:
Sarcoma
Year:
2013
Journal volume:
2013
Pages contribution:
404962
Language:
eng
Fulltext / DOI:
doi:10.1155/2013/404962
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24369449
Print-ISSN:
1357-714X
TUM Institution:
Klinik und Poliklinik für Orthopädie und Sportorthopädie
 BibTeX