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Title:

Behavior of primary human osteoblasts on trimmed and sandblasted Ti6Al4V surfaces functionalized with integrin ?v?3-selective cyclic RGD peptides.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Mas-Moruno, C; Dorfner, PM; Manzenrieder, F; Neubauer, S; Reuning, U; Burgkart, R; Kessler, H
Abstract:
It is well known that functionalization of surfaces with cell adhesive peptides mimicking the integrin binding motif of extracellular matrix proteins is a feasible approach to improve osseointegration of implant materials. Also, modification of the surface properties of the material (e.g., roughness) strongly influences cell behavior. However, these two approaches are rarely studied together. This study addressed the hypothesis that the combination of peptide functionalization and surface roughn...     »
Journal title abbreviation:
J Biomed Mater Res A
Year:
2013
Journal volume:
101
Journal issue:
1
Pages contribution:
87-97
Language:
eng
Fulltext / DOI:
doi:10.1002/jbm.a.34303
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22826207
Print-ISSN:
1549-3296
TUM Institution:
Frauenklinik und Poliklinik; Klinik und Poliklinik für Orthopädie und Sportorthopädie
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