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Title:

Revacept, a Novel Inhibitor of Platelet Adhesion, in Patients Undergoing Elective PCI-Design and Rationale of the Randomized ISAR-PLASTER Trial.

Document type:
Journal Article
Author(s):
Schüpke, Stefanie; Hein-Rothweiler, Ralph; Mayer, Katharina; Janisch, Marion; Sibbing, Dirk; Ndrepepa, Gjin; Hilz, Raphaela; Laugwitz, Karl-Ludwig; Bernlochner, Isabell; Gschwendtner, Sarah; Kupka, Danny; Gori, Tommaso; Zeiher, Andreas M; Schunkert, Heribert; Massberg, Steffen; Kastrati, Adnan
Abstract:
Despite dual antiplatelet therapy patients undergoing percutaneous coronary intervention (PCI) continue to experience periprocedural ischemic events. In addition, all currently used antithrombotic drugs increase the bleeding risk. Thus, there is an unmet clinical need for antithrombotic strategies with improved efficacy and no increase in bleeding. Revacept is a novel, lesion-directed antithrombotic drug that does not interfere with the function of circulating platelets. This dimeric fusion prot...     »
Journal title abbreviation:
Thromb Haemost
Year:
2019
Journal volume:
119
Journal issue:
9
Pages contribution:
1539-1545
Fulltext / DOI:
doi:10.1055/s-0039-1692423
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31226721
Print-ISSN:
0340-6245
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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