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Titel:

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.

Dokumenttyp:
Article; Journal Article
Autor(en):
Ferraro, Bartolo; Leoni, Giovanna; Hinkel, Rabea; Ormanns, Steffen; Paulin, Nicole; Ortega-Gomez, Almudena; Viola, Joana R; de Jong, Renske; Bongiovanni, Dario; Bozoglu, Tarik; Maas, Sanne L; D'Amico, Michele; Kessler, Thorsten; Zeller, Tanja; Hristov, Michael; Reutelingsperger, Chris; Sager, Hendrik B; Döring, Yvonne; Nahrendorf, Matthias; Kupatt, Christian; Soehnlein, Oliver
Abstract:
BACKGROUND: Heart failure following myocardial infarction (MI) remains one of the major causes of death worldwide, and its treatment is a crucial challenge of cardiovascular medicine. An attractive therapeutic strategy is to stimulate endogenous mechanisms of myocardial regeneration. OBJECTIVES: This study evaluates the potential therapeutic treatment with annexin A1 (AnxA1) to induce cardiac repair after MI. METHODS: AnxA1 knockout (AnxA1-/-) and wild-type mice underwent MI induced by ligation...     »
Zeitschriftentitel:
J Am Coll Cardiol
Jahr:
2019
Band / Volume:
73
Heft / Issue:
23
Seitenangaben Beitrag:
2990-3002
Volltext / DOI:
doi:10.1016/j.jacc.2019.03.503
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31196457
Print-ISSN:
0735-1097
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie); Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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