Benutzer: Gast  Login
Mehr Felder
Einfache Suche
Titel:

The Epstein-Barr Virus Major Tegument Protein BNRF1 Is a Common Target of Cytotoxic CD4+ T Cells.

Dokumenttyp:
Article; Journal Article
Autor(en):
Adhikary, Dinesh; Damaschke, Julia; Mautner, Josef; Behrends, Uta
Abstract:
Cellular immunotherapy is a proven approach against Epstein-Barr virus (EBV)-driven lymphoproliferation in recipients of hematopoietic stem cells. Extending the applicability and improving the response rates of such therapy demands improving the knowledge base. We studied 23 healthy donors for specific CD4+ T cell responses against the viral tegument protein BNRF1 and found such T cells in all seropositive donors, establishing BNRF1 as an important immune target in EBV. We identified 18 novel im...     »
Zeitschriftentitel:
J Virol
Jahr:
2020
Band / Volume:
94
Heft / Issue:
15
Volltext / DOI:
doi:10.1128/JVI.00284-20
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32461311
Print-ISSN:
0022-538X
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
 BibTeX