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Titel:

Establishment and effects of allograft and synthetic bone graft substitute treatment of a critical size metaphyseal bone defect model in the sheep femur.

Dokumenttyp:
Article; Journal Article
Autor(en):
Hettwer, Werner; Horstmann, Peter F; Bischoff, Sabine; Güllmar, Daniel; Reichenbach, Jürgen R; Poh, Patrina S P; Van Griensven, Martijn; Gras, Florian; Diefenbeck, Michael
Abstract:
Assessment of bone graft material efficacy is difficult in humans, since invasive methods like staged CT scans or biopsies are ethically unjustifiable. Therefore, we developed a novel large animal model for the verification of a potential transformation of synthetic bone graft substitutes into vital bone. The model combines multiple imaging methods with corresponding histology in standardized critical sized cancellous bone defect. Cylindrical bone voids (10 ml) were created in the medial femoral...     »
Zeitschriftentitel:
APMIS
Jahr:
2019
Band / Volume:
127
Heft / Issue:
2
Seitenangaben Beitrag:
53-63
Volltext / DOI:
doi:10.1111/apm.12918
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30698307
Print-ISSN:
0903-4641
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie
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