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Title:

CNS-targeting pharmacological interventions for the metabolic syndrome.

Document type:
Journal Article; Review
Author(s):
Stemmer, Kerstin; Müller, Timo D; DiMarchi, Richard D; Pfluger, Paul T; Tschöp, Matthias H
Abstract:
The metabolic syndrome (MetS) encompasses medical conditions such as obesity, hyperglycemia, high blood pressure, and dyslipidemia that are major drivers for the ever-increasing prevalence of type 2 diabetes, cardiovascular diseases, and certain types of cancer. At the core of clinical strategies against the MetS is weight loss, induced by bariatric surgery, lifestyle changes based on calorie reduction and exercise, or pharmacology. This Review summarizes the past, current, and future efforts of...     »
Journal title abbreviation:
J Clin Invest
Year:
2019
Journal volume:
130
Fulltext / DOI:
doi:10.1172/JCI129195
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31380808
Print-ISSN:
0021-9738
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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