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Dokumenttyp:
Journal Article
Autor(en):
Niu, Lili; Geyer, Philipp E; Wewer Albrechtsen, Nicolai J; Gluud, Lise L; Santos, Alberto; Doll, Sophia; Treit, Peter V; Holst, Jens J; Knop, Filip K; Vilsbøll, Tina; Junker, Anders; Sachs, Stephan; Stemmer, Kerstin; Müller, Timo D; Tschöp, Matthias H; Hofmann, Susanna M; Mann, Matthias
Titel:
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease.
Abstract:
Non-alcoholic fatty liver disease (NAFLD) affects 25% of the population and can progress to cirrhosis with limited treatment options. As the liver secretes most of the blood plasma proteins, liver disease may affect the plasma proteome. Plasma proteome profiling of 48 patients with and without cirrhosis or NAFLD revealed six statistically significantly changing proteins (ALDOB, APOM, LGALS3BP, PIGR, VTN, and AFM), two of which are already linked to liver disease. Polymeric immunoglobulin recepto...     »
Zeitschriftentitel:
Mol Syst Biol
Jahr:
2019
Band / Volume:
15
Heft / Issue:
3
Volltext / DOI:
doi:10.15252/msb.20188793
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30824564
Print-ISSN:
1744-4292
TUM Einrichtung:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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