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Title:

Chip-based sensing for release of unprocessed cell surface proteins in vitro and in serum and its (patho)physiological relevance.

Document type:
Journal Article
Author(s):
Müller, Günter A; Herling, Andreas W; Stemmer, Kerstin; Lechner, Andreas; Tschöp, Matthias H
Abstract:
To study the possibility that certain components of eukaryotic plasma membranes are released under certain (patho)physiological conditions, a chip-based sensor was developed for the detection of cell surface proteins, which are anchored at the outer leaflet of eukaryotic plasma membranes by a covalently attached glycolipid, exclusively, and might be prone to spontaneous or regulated release on the basis of their amphiphilic character. For this, unprocessed, full-length glycosylphosphatidylinosit...     »
Journal title abbreviation:
Am J Physiol Endocrinol Metab
Year:
2019
Journal volume:
317
Journal issue:
2
Pages contribution:
E212-E233
Fulltext / DOI:
doi:10.1152/ajpendo.00079.2019
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31039006
Print-ISSN:
0193-1849
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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