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Titel:

Glucagon-like peptide 1 (GLP-1)

Dokumenttyp:
Review
Autor(en):
Mueller, T. D.; Finan, B.; Bloom, S. R.; D'Alessio, D.; Drucker, D. J.; Flatt, P. R.; Fritsche, A.; Gribble, F.; Grill, H. J.; Habener, J. F.; Holst, J. J.; Langhans, W.; Meier, J. J.; Nauck, M. A.; Perez-Tilve, D.; Pocai, A.; Reimann, F.; Sandoval, D. A.; Schwartz, T. W.; Seeley, R. J.; Stemmer, K.; Tang-Christensen, M.; Woods, S. C.; DiMarchi, R. D.; Tschoep, M. H.
Abstract:
Background: The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose-dependent stimulation of insulin secretion, decrease of gastric emptying, inhibition of food intake, increase of natriuresis and diuresis, and modulation of rodent beta-cell proliferation. GLP-1 also has cardio- and neuroprotective effects, decreases inflammation and apoptosis, and has implications for learning and memory, r...     »
Zeitschriftentitel:
Mol. Metab.
Jahr:
2019
Band / Volume:
30
Seitenangaben Beitrag:
72-130
Volltext / DOI:
doi:10.1016/j.molmet.2019.09.010
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31767182
Print-ISSN:
2212-8778
TUM Einrichtung:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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