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Title:

Hepatic lipid droplet homeostasis and fatty liver disease.

Document type:
Journal Article; Review
Author(s):
Seebacher, Fabian; Zeigerer, Anja; Kory, Nora; Krahmer, Natalie
Abstract:
In cells, lipids are stored in lipid droplets, dynamic organelles that adapt their size, abundance, lipid and protein composition and organelle interactions to metabolic changes. Lipid droplet accumulation in the liver is the hallmark of non-alcoholic fatty liver disease (NAFLD). Due to the prevalence of obesity, the strongest risk factor for steatosis, NAFLD and its associated complications are currently affecting more than 1 billion people worldwide. Here, we review how triglyceride and phosph...     »
Journal title abbreviation:
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Year:
2020
Journal volume:
108
Pages contribution:
72-81
Fulltext / DOI:
doi:10.1016/j.semcdb.2020.04.011
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32444289
Print-ISSN:
1084-9521
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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