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Titel:

Hepatic lipid droplet homeostasis and fatty liver disease.

Dokumenttyp:
Journal Article; Review
Autor(en):
Seebacher, Fabian; Zeigerer, Anja; Kory, Nora; Krahmer, Natalie
Abstract:
In cells, lipids are stored in lipid droplets, dynamic organelles that adapt their size, abundance, lipid and protein composition and organelle interactions to metabolic changes. Lipid droplet accumulation in the liver is the hallmark of non-alcoholic fatty liver disease (NAFLD). Due to the prevalence of obesity, the strongest risk factor for steatosis, NAFLD and its associated complications are currently affecting more than 1 billion people worldwide. Here, we review how triglyceride and phosph...     »
Zeitschriftentitel:
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Jahr:
2020
Band / Volume:
108
Seitenangaben Beitrag:
72-81
Volltext / DOI:
doi:10.1016/j.semcdb.2020.04.011
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32444289
Print-ISSN:
1084-9521
TUM Einrichtung:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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