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Titel:

Integrin ß1 polymorphisms and bleeding risk after coronary artery stenting.

Dokumenttyp:
Journal Article
Autor(en):
Thienel, M; Lüsebrink, E; Kastrati, A; Dannenberg, L; Polzin, A; Schulz, C; Massberg, S; Petzold, T
Abstract:
Bleeding complications following percutaneous coronary intervention associate with increased mortality. However, the underlying molecular mechanisms are insufficiently understood. Platelet recruitment and activation at sites of vascular injury depends on the function of integrin adhesion receptors. Besides GPIIbIIIa as the most abundant integrin receptor, platelets relevantly express ß1 integrins. Experimental evidence from in vivo studies suggests a significant role of ß1 integrins in primary h...     »
Zeitschriftentitel:
Mol Biol Rep
Jahr:
2019
Band / Volume:
46
Heft / Issue:
6
Seitenangaben Beitrag:
5695-5702
Volltext / DOI:
doi:10.1007/s11033-019-05003-2
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31359383
Print-ISSN:
0301-4851
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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