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Titel:

Psoriasis Pathogenesis: Keratinocytes Are Back in the Spotlight.

Dokumenttyp:
Journal Article; Comment
Autor(en):
Garzorz-Stark, Natalie; Eyerich, Kilian
Abstract:
Psoriasis is a T helper type 17-mediated immune disease. Initial triggers that lead to T helper type 17 production and inflammatory cell recruitment into skin are being delineated. Autoantigens that stimulate T helper type 17 cells are also being identified. A new and important piece of the puzzle indicates that keratinocytes not only amplify inflammation, but that they are essential for a full-blown IL-17-mediated psoriatic phenotype in mice.
Zeitschriftentitel:
J Invest Dermatol
Jahr:
2019
Band / Volume:
139
Heft / Issue:
5
Seitenangaben Beitrag:
995-996
Volltext / DOI:
doi:10.1016/j.jid.2019.01.026
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31010530
Print-ISSN:
0022-202X
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
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