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Document type:
Journal Article 
Author(s):
Hoelscher, Sarah C; Stich, Theresia; Diehm, Anne; Lahm, Harald; Dreßen, Martina; Zhang, Zhong; Neb, Irina; Aherrahrou, Zouhair; Erdmann, Jeanette; Schunkert, Heribert; Santamaria, Gianluca; Cuda, Giovanni; Gilsbach, Ralf; Hein, Lutz; Lange, Rüdiger; Hassel, David; Krane, Markus; Doppler, Stefanie A 
Title:
miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations. 
Abstract:
MicroRNAs (miRs) appear to be major, yet poorly understood players in regulatory networks guiding cardiogenesis. We sought to identify miRs with unknown functions during cardiogenesis analyzing the miR-profile of multipotent Nkx2.5 enhancer cardiac progenitor cells (NkxCE-CPCs). Besides well-known candidates such as miR-1, we found about 40 miRs that were highly enriched in NkxCE-CPCs, four of which were chosen for further analysis. Knockdown in zebrafish revealed that only miR-128a affected car...    »
 
Journal title abbreviation:
Int J Mol Sci 
Year:
2020 
Journal volume:
21 
Journal issue:
Fulltext / DOI:
Print-ISSN:
1422-0067 
TUM Institution:
Arbeitsgruppe Tissue Engineering und Regenerative Medizin; Klinik für Herz- und Gefäßchirurgie (Prof. Lange)