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Title:

Enoxaparin and rivaroxaban have different effects on human mesenchymal stromal cells in the early stages of bone healing.

Document type:
Journal Article
Author(s):
Pilge, H; Fröbel, J; Prodinger, P M; Mrotzek, S J; Fischer, J C; Zilkens, C; Bittersohl, B; Krauspe, R
Abstract:
Venous thromboembolism (VTE) is a major potential complication following orthopaedic surgery. Subcutaneously administered enoxaparin has been used as the benchmark to reduce the incidence of VTE. However, concerns have been raised regarding the long-term administration of enoxaparin and its possible negative effects on bone healing and bone density with an increase of the risk of osteoporotic fractures. New oral anticoagulants such as rivaroxaban have recently been introduced, however, there is...     »
Journal title abbreviation:
Bone Joint Res
Year:
2016
Journal volume:
5
Journal issue:
3
Pages contribution:
95-100
Language:
eng
Fulltext / DOI:
doi:10.1302/2046-3758.53.2000595
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26989119
TUM Institution:
Klinik und Poliklinik für Orthopädie und Sportorthopädie
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