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Titel:

Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Op den Brouw, ML; Binda, RS; van Roosmalen, MH; Protzer, U; Janssen, HL; van der Molen, RG; Woltman, AM
Abstract:
Chronic hepatitis B virus (HBV) infection is the result of an inadequate immune response towards the virus. Myeloid dendritic cells (mDC) of patients with chronic HBV are impaired in their maturation and function, resulting in more tolerogenic rather than immunogenic responses, which may contribute to viral persistence. The mechanism responsible for altered mDC function remains unclear. The HBV-infected patients display large amounts of HBV particles and viral proteins in their circulation, espe...     »
Zeitschriftentitel:
Immunology
Jahr:
2009
Band / Volume:
126
Heft / Issue:
2
Seitenangaben Beitrag:
280-9
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1365-2567.2008.02896.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18624732
Print-ISSN:
0019-2805
TUM Einrichtung:
Institut für Virologie
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