User: Guest  Login
Title:

Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Levin, A; Hayouka, Z; Helfer, M; Brack-Werner, R; Friedler, A; Loyter, A
Abstract:
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) integrase protein (IN), catalyzes the integration of viral DNA into the host cell genome. IN catalyzes the first step of the integration process, namely the 3'-end processing in which IN removes a pGT dinucleotide from the 3' end of each viral long terminal repeat (LTR). Following nuclear import of the viral preintegration complex, the host chromosomal DNA becomes accessible to the viral cDNA and the second step of the integration proce...     »
Journal title abbreviation:
PLoS ONE
Year:
2009
Journal volume:
4
Journal issue:
1
Pages contribution:
e4155
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0004155
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19127291
Print-ISSN:
1932-6203
TUM Institution:
Institut für Virologie
 BibTeX