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Title:

Drosophila alpha-1,4-glycosyltransferase (alpha-4GT1) inhibits reaper-mediated apoptosis in the eye.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Protzer, CE; Preiss, A; Nagel, AC
Abstract:
In a genetic screen, alpha-4GT1 has been identified as a potential enhancer of Hairless-mediated cell death in the eye of Drosophila. alpha-4GT1 encodes an alpha-1,4-glycosyltransferase, known to catalyze the fifth step in a series of ceramide glycosylation events. As reported for other enzymes involved in the glycosylation of ceramide, alpha-4GT1 is strongly expressed during oogenesis and is deposited maternally in the egg. Moreover, the protein is enriched at cell membranes. Unexpectedly, over...     »
Journal title abbreviation:
Cell Tissue Res
Year:
2009
Journal volume:
336
Journal issue:
1
Pages contribution:
149-58
Language:
eng
Fulltext / DOI:
doi:10.1007/s00441-009-0758-1
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19252929
Print-ISSN:
0302-766X
TUM Institution:
Institut für Virologie
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