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Document type:
Journal Article; Article
Author(s):
Higuchi, T; Anton, M; Dumler, K; Seidl, S; Pelisek, J; Saraste, A; Welling, A; Hofmann, F; Oostendorp, RA; Gansbacher, B; Nekolla, SG; Bengel, FM; Botnar, RM; Schwaiger, M
Title:
Combined reporter gene PET and iron oxide MRI for monitoring survival and localization of transplanted cells in the rat heart.
Abstract:
There is a need for in vivo monitoring of cell engraftment and survival after cardiac cell transplantation therapy. This study assessed the feasibility and usefulness of combined PET and MRI for monitoring cell engraftment and survival after cell transplantation. METHODS: Human endothelial progenitor cells (HEPCs), derived from CD34+ mononuclear cells of umbilical cord blood, were retrovirally transduced with the sodium iodide symporter (NIS) gene for reporter gene imaging by (124)I-PET and labe...    »
Journal title abbreviation:
J Nucl Med
Year:
2009
Journal volume:
50
Journal issue:
7
Pages contribution:
1088-94
Language:
eng
Fulltext / DOI:
doi:10.2967/jnumed.108.060665
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19525455
Print-ISSN:
0161-5505
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein); III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Experimentelle Onkologie und Therapieforschung; Institut für Pharmakologie und Toxikologie; Klinik und Poliklinik für Nuklearmedizin
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