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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Marcinowski, L; Lidschreiber, M; Windhager, L; Rieder, M; Bosse, JB; Rädle, B; Bonfert, T; Györy, I; de Graaf, M; Prazeres da Costa, O; Rosenstiel, P; Friedel, CC; Zimmer, R; Ruzsics, Z; Dölken, L 
Title:
Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection. 
Abstract:
During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging) to dissect the real-time kinetics of cellular and viral transcriptional activity during lytic murine cytomegalovirus (MCMV) infection. Microarray profiling on newly transcribed RNA obtained at different times during the first six hours of MCMV infection revealed discr...    »
 
Journal title abbreviation:
PLoS Pathog 
Year:
2012 
Journal volume:
Journal issue:
Pages contribution:
e1002908 
Language:
eng 
Print-ISSN:
1553-7366 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene 
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