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Document type:
Journal Article; Article
Author(s):
Ried, JS; Döring, A; Oexle, K; Meisinger, C; Winkelmann, J; Klopp, N; Meitinger, T; Peters, A; Suhre, K; Wichmann, HE; Gieger, C
Title:
PSEA: Phenotype Set Enrichment Analysis-A New Method for Analysis of Multiple Phenotypes.
Abstract:
Most genome-wide association studies (GWAS) are restricted to one phenotype, even if multiple related or unrelated phenotypes are available. However, an integrated analysis of multiple phenotypes can provide insight into their shared genetic basis and may improve the power of association studies. We present a new method, called "phenotype set enrichment analysis" (PSEA), which uses ideas of gene set enrichment analysis for the investigation of phenotype sets. PSEA combines statistics of univaria...     »
Journal title abbreviation:
Genet Epidemiol
Year:
2012
Journal volume:
36
Journal issue:
3
Pages contribution:
244-52
Language:
eng
Fulltext / DOI:
doi:10.1002/gepi.21617
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22714936
Print-ISSN:
0741-0395
TUM Institution:
Institut für Humangenetik; Neurologische Klinik und Poliklinik
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