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Title:

Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Roth, Susanne; Ruland, Jürgen
Abstract:
Caspase recruitment domain-containing protein (Card)9 is a nonredundant adapter protein that functions in the innate immune system in the assembly of multifunctional signaling complexes. Together with B cell lymphoma (Bcl)10 and the paracaspase, mucosa-associated lymphoid tissue lymphoma translocation protein (Malt)1, Card9 links spleen-tyrosine kinase (Syk)-coupled C-type lectin receptors to inflammatory responses. Card9 signaling also responds to intracellular danger sensors, such as retinoic...     »
Journal title abbreviation:
Trends Immunol
Year:
2013
Journal volume:
34
Journal issue:
6
Pages contribution:
243-50
Language:
eng
Fulltext / DOI:
doi:10.1016/j.it.2013.02.006
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23523010
Print-ISSN:
1471-4906
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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