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Title:

CD44 and OTP are strong prognostic markers for pulmonary carcinoids.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Swarts, DR; Henfling, ME; Van Neste, L; van Suylen, RJ; Dingemans, AM; Dinjens, WN; Haesevoets, A; Rudelius, M; Thunnissen, E; Volante, M; Van Criekinge, W; Van Engeland, M; Ramaekers, FC; Speel, EJ
Abstract:
Pulmonary carcinoids are well-differentiated neuroendocrine tumors showing usually a favorable prognosis. However, there is a risk for late recurrence and/or distant metastasis. Because histologic classification in typical and atypical carcinoids is difficult and its reliability to predict disease outcome varies, we evaluated three genes as potential prognostic markers, that is, orthopedia homeobox (OTP), CD44, and rearranged during transfection (RET).These genes were analyzed in 56 frozen carci...     »
Journal title abbreviation:
Clin Cancer Res
Year:
2013
Journal volume:
19
Journal issue:
8
Pages contribution:
2197-207
Language:
eng
Fulltext / DOI:
doi:10.1158/1078-0432.CCR-12-3078
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23444222
Print-ISSN:
1078-0432
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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