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Title:

Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Derycke, Lara; Eyerich, Stefanie; Van Crombruggen, Koen; Pérez-Novo, Claudina; Holtappels, Gabriele; Deruyck, Natalie; Gevaert, Philippe; Bachert, Claus
Abstract:
In chronic rhinosinusitis (CRS) different phenotypes have been reported based on cytokine profile and inflammatory cell patterns. The aim of this study was to characterize the intracytoplasmatic cytokines of T cells infiltrating the inflamed sinonasal mucosa.Infiltrated T cells and tissue homogenates from sinonasal mucosal samples of 7 healthy subjects, 9 patients with CRS without nasal polyp (CRSsNP), 15 with CRS with nasal polyps (CRSwNP) and 5 cystic fibrosis patients (CF-NP) were analyzed fo...     »
Journal title abbreviation:
PLoS ONE
Year:
2014
Journal volume:
9
Journal issue:
6
Pages contribution:
e97581
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0097581
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24911279
Print-ISSN:
1932-6203
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
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