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Title:

Genotype analysis in Hungarian patients with multiple primary melanoma.

Document type:
journal article
Author(s):
Hatvani, Zsófia, Z; Brodszky, Valentin, V; Mazán, Mercédesz, M; Pintér, Dóra, D; Hársing, Judit, J; Tóth, Veronika, V; Somlai, Beáta, B; Kárpáti, Sarolta, S
Abstract:
Multiple primary melanoma patients (MPMps) have better prognosis and are more prone to genetic predisposition than single melanoma patients. We aimed to compare genetic background (CDKN2A, CDK4, MITF, MC1R) of 43 Hungarian MPMps with their clinicopathological data. We observed a higher rate of synchronous first and second melanoma (MM) (49%) and a higher frequency of non-melanoma tumor co-occurrence (42%) than reported previously. CDKN2A mutation frequency was 4.7% (E69G, R99P). We identified a...     »
Journal title abbreviation:
Exp Dermatol
Year:
2014
Journal volume:
23
Journal issue:
5
Pages contribution:
361-4
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24660985
Print-ISSN:
0906-6705
TUM Institution:
Institut für Radiologie
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