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Titel:

Phospholipase D1 is involved in ?1-adrenergic contraction of murine vascular smooth muscle.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Wegener, Jörg W; Loga, Florian; Stegner, David; Nieswandt, Bernhard; Hofmann, Franz
Abstract:
?1-Adrenergic stimulation increases blood vessel tone in mammals. This process involves a number of intracellular signaling pathways that include signaling via phospholipase C, diacylglycerol (DAG), and protein kinase C. So far, it is not certain whether signaling via phospholipase D (PLD) and PLD-derived DAG is involved in this process. We asked whether PLD participates in the ?1-adrenergic-mediated signaling in vascular smooth muscle. ?1-Adrenergic-induced contraction was assessed by myography...     »
Zeitschriftentitel:
FASEB J
Jahr:
2014
Band / Volume:
28
Heft / Issue:
3
Seitenangaben Beitrag:
1044-8
Sprache:
eng
Volltext / DOI:
doi:10.1096/fj.13-237925
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24253251
Print-ISSN:
0892-6638
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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