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Titel:

Cortical control of adaptation and sensory relay mode in the thalamus.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Mease, Rebecca A; Krieger, Patrik; Groh, Alexander
Abstract:
A major synaptic input to the thalamus originates from neurons in cortical layer 6 (L6); however, the function of this cortico-thalamic pathway during sensory processing is not well understood. In the mouse whisker system, we found that optogenetic stimulation of L6 in vivo results in a mixture of hyperpolarization and depolarization in the thalamic target neurons. The hyperpolarization was transient, and for longer L6 activation (>200 ms), thalamic neurons reached a depolarized resting membran...     »
Zeitschriftentitel:
Proc Natl Acad Sci U S A
Jahr:
2014
Band / Volume:
111
Heft / Issue:
18
Seitenangaben Beitrag:
6798-803
Sprache:
eng
Volltext / DOI:
doi:10.1073/pnas.1318665111
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24748112
Print-ISSN:
0027-8424
TUM Einrichtung:
Institut für Neurowissenschaften
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