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Title:

Multifunctional photosensitizer-based contrast agents for photoacoustic imaging.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Ho, Chris Jun Hui; Balasundaram, Ghayathri; Driessen, Wouter; McLaren, Ross; Wong, Chi Lok; Dinish, U S; Attia, Amalina Binte Ebrahim; Ntziachristos, Vasilis; Olivo, Malini
Abstract:
Photoacoustic imaging is a novel hybrid imaging modality combining the high spatial resolution of optical imaging with the high penetration depth of ultrasound imaging. Here, for the first time, we evaluate the efficacy of various photosensitizers that are widely used as photodynamic therapeutic (PDT) agents as photoacoustic contrast agents. Photoacoustic imaging of photosensitizers exhibits advantages over fluorescence imaging, which is prone to photobleaching and autofluorescence interference....     »
Journal title abbreviation:
Sci Rep
Year:
2014
Journal volume:
4
Pages contribution:
5342
Language:
eng
Fulltext / DOI:
doi:10.1038/srep05342
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24938638
Print-ISSN:
2045-2322
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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