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Title:

Correlation of biomechanics to tissue reaction in aortic aneurysms assessed by finite elements and [18F]-fluorodeoxyglucose-PET/CT

Document type:
Zeitschriftenaufsatz
Author(s):
Maier, A.; Essler, M.; Gee, M.W.; Eckstein, H.-H.; Wall, W.A.; Reeps, C.
Abstract:
Mechanobiological interactions are essential for the adaption of the cardiovascular system to altered environmental and internal conditions, but are poorly understood with regard to abdominal aortic aneurysm (AAA) pathogenesis, growth and rupture. In the present study, we therefore calculated mechanical AAA quantities using nonlinear finite element methods and correlated these to [18F]-fluorodeoxyglucose (FDG)-metabolic activity in the AAA wall detected by positron emission tomography/computed...     »
Keywords:
abdominal aortic aneurysm; finite element analysis; FDG-PET/CT; inflammation; mechanotransduction; metabolic activity
Dewey Decimal Classification:
620 Ingenieurwissenschaften
Journal title:
International Journal for Numerical Methods in Biomedical Engineering
Year:
2012
Journal volume:
28
Journal issue:
4
Pages contribution:
456-471
Covered by:
Web of Science
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1002/cnm.1477
Status:
Verlagsversion / published
Semester:
SS 12
Format:
Text
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