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Title:

A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas.

Document type:
Journal Article
Author(s):
Slotta-Huspenina, J; Wolff, C; Drecoll, E; Feith, M; Bettstetter, M; Malinowsky, K; Bauer, L; Becker, K; Ott, K; Höfler, H; Becker, KF; Langer, R
Abstract:
Background:Oesophageal adenocarcinomas often show resistances to chemotherapy (CTX), therefore, it would be of high interest to better understand the mechanisms of resistance. We examined the expression of heat-shock proteins (HSPs) and glucose-regulated proteins (GRPs) in pretherapeutic biopsies of oesophageal adenocarcinomas to assess their potential role in CTX response.Methods:Ninety biopsies of locally advanced adenocarcinomas before platin/5-fluorouracil (FU)-based CTX were investigated by...     »
Journal title abbreviation:
Br J Cancer
Year:
2013
Journal volume:
109
Journal issue:
2
Pages contribution:
370-8
Language:
eng
Fulltext / DOI:
doi:10.1038/bjc.2013.319
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23839491
Print-ISSN:
0007-0920
TUM Institution:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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