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Titel:

The role of dendritic cells in autoimmunity.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
Autor(en):
Ganguly, Dipyaman; Haak, Stefan; Sisirak, Vanja; Reizis, Boris
Abstract:
Dendritic cells (DCs) initiate and shape both the innate and adaptive immune responses. Accordingly, recent evidence from clinical studies and experimental models implicates DCs in the pathogenesis of most autoimmune diseases. However, fundamental questions remain unanswered concerning the actual roles of DCs in autoimmunity, both in general and, in particular, in specific diseases. In this Review, we discuss the proposed roles of DCs in immunological tolerance, the effect of the gain or loss of...     »
Zeitschriftentitel:
Nat Rev Immunol
Jahr:
2013
Band / Volume:
13
Heft / Issue:
8
Seitenangaben Beitrag:
566-77
Sprache:
eng
Volltext / DOI:
doi:10.1038/nri3477
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23827956
Print-ISSN:
1474-1733
TUM Einrichtung:
Molekulare Allergologie (Prof. Schmidt-Weber)
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