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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Taruttis, Adrian; Morscher, Stefan; Burton, Neal C; Razansky, Daniel; Ntziachristos, Vasilis 
Title:
Fast multispectral optoacoustic tomography (MSOT) for dynamic imaging of pharmacokinetics and biodistribution in multiple organs. 
Abstract:
The characterization of pharmacokinetic and biodistribution profiles is an essential step in the development process of new candidate drugs or imaging agents. Simultaneously, the assessment of organ function related to the uptake and clearance of drugs is of great importance. To this end, we demonstrate an imaging platform capable of high-rate characterization of the dynamics of fluorescent agents in multiple organs using multispectral optoacoustic tomography (MSOT). A spatial resolution of appr...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2012 
Journal volume:
Journal issue:
Pages contribution:
e30491 
Language:
eng 
Print-ISSN:
1932-6203 
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)