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Title:

Ultrafine particles affect the balance of endogenous pro- and anti-inflammatory lipid mediators in the lung: in-vitro and in-vivo studies.

Document type:
Journal Article
Author(s):
Beck-Speier, I; Karg, E; Behrendt, H; Stoeger, T; Alessandrini, F
Abstract:
Exposure to ultrafine particles exerts diverse harmful effects including aggravation of pulmonary diseases like asthma. Recently we demonstrated in a mouse model for allergic airway inflammation that particle-derived oxidative stress plays a crucial role during augmentation of allergen-induced lung inflammation by ultrafine carbon particle (UfCP) inhalation. The mechanisms how particle inhalation might change the inflammatory balance in the lungs, leading to accelerated inflammatory reactions, r...     »
Journal title abbreviation:
Part Fibre Toxicol
Year:
2012
Journal volume:
9
Pages contribution:
27
Language:
eng
Fulltext / DOI:
doi:10.1186/1743-8977-9-27
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22809365
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
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