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Title:

Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge.

Document type:
Journal Article
Author(s):
Schulze, J; Voss, S; Zissler, U; Rose, MA; Zielen, S; Schubert, R
Abstract:
ABSTRACT:Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma. However, clinical symptoms are less likely to be induced. Therefore, we designed a protocol for repetitive high-dose bronchial allergen challenges to generate clinical symptoms and airway inflammation.A total of 27 patients aged 18 to 40 years with positive skin-prick tests and mild asthma underwent repetitive hi...     »
Journal title abbreviation:
Respir Res
Year:
2012
Journal volume:
13
Pages contribution:
78
Language:
eng
Fulltext / DOI:
doi:10.1186/1465-9921-13-78
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22989372
Print-ISSN:
1465-9921
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
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