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Title:

What do cells regulate in soft tissues on short time scales?

Document type:
Zeitschriftenaufsatz
Author(s):
Eichinger JF, Paukner D, Aydin RC, Wall WA, Humphrey JD, Cyron CJ
Abstract:
Cells within living soft biological tissues seem to promote the maintenance of a mechanical state within adefined range near a so-called set-point. This mechanobiological process is often referred to as mechanicalhomeostasis. During this process, cells intimately interact with the fibers of the surrounding extracellularmatrix (ECM). It remains poorly understood, however, what individual cells actually regulate during theseinteractions, and how these micromechanical regulations are translated t...     »
Keywords:
homeostasis, mechanosensation, mechanoregulation, cell-matrix interactions, discrete fibermodel
Dewey Decimal Classification:
620 Ingenieurwissenschaften
Journal title:
Acta Biomaterialia
Year:
2021
Year / month:
2021-04
Fulltext / DOI:
doi:10.1016/j.actbio.2021.07.054
Status:
Preprint / submitted
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