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Title:

Combined Immunohistochemistry after Mass Spectrometry Imaging for Superior Spatial Information.

Document type:
Journal Article
Author(s):
Kriegsmann, Katharina; Longuespée, Rémi; Hundemer, Michael; Zgorzelski, Christiane; Casadonte, Rita; Schwamborn, Kristina; Weichert, Wilko; Schirmacher, Peter; Harms, Alexander; Kazdal, Daniel; Leichsenring, Jonas; Stenzinger, Albrecht; Warth, Arne; Fresnais, Margaux; Kriegsmann, Jörg; Kriegsmann, Mark
Abstract:
Tissue slides analyzed by MS imaging (MSI) are stained by H&E; (Haematoxylin and Eosin) to identify regions of interest. As it can be difficult to identify specific cells of interest by H&E; alone, data analysis may be impaired. Immunohistochemistry (IHC) can highlight cells of interest but single or combined IHC on tissue sections analyzed by MSI have not been performed.We performed MSI on bone marrow biopsies from patients with multiple myeloma and stained different antibodies (CD38, CD138, MUM1,...     »
Journal title abbreviation:
Proteomics Clin Appl
Year:
2019
Journal volume:
13
Journal issue:
1
Pages contribution:
e1800035
Language:
eng
Fulltext / DOI:
doi:10.1002/prca.201800035
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30035857
Print-ISSN:
1862-8346
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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