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Title:

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).

Document type:
Journal Article
Author(s):
Johnen, Andreas; Bürkner, Paul-Christian; Landmeyer, Nils C; Ambrosius, Björn; Calabrese, Pasquale; Motte, Jeremias; Hessler, Nicole; Antony, Gisela; König, Inke R; Klotz, Luisa; Hoshi, Muna-Miriam; Aly, Lilian; Groppa, Sergiu; Luessi, Felix; Paul, Friedemann; Tackenberg, Björn; Bergh, Florian Then; Kümpfel, Tania; Tumani, Hayrettin; Stangel, Martin; Weber, Frank; Bayas, Antonios; Wildemann, Brigitte; Heesen, Christoph; Zettl, Uwe K; Zipp, Frauke; Hemmer, Bernhard; Meuth, Sven G; Gold, Ralf; Wie...     »
Abstract:
BACKGROUND: Cognitive impairment (CI) affects approximately one-third of the patients with early multiple sclerosis (MS) and clinically isolated syndrome (CIS). Little is known about factors predicting CI and progression after initial diagnosis. METHODS: Neuropsychological screening data from baseline and 1-year follow-up of a prospective multicenter cohort study (NationMS) involving 1123 patients with newly diagnosed MS or CIS were analyzed. Employing linear multilevel models, we investigated w...     »
Journal title abbreviation:
J Neurol
Year:
2019
Journal volume:
266
Journal issue:
2
Pages contribution:
386-397
Language:
eng
Fulltext / DOI:
doi:10.1007/s00415-018-9142-y
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30515631
Print-ISSN:
0340-5354
TUM Institution:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik
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