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Title:

A Visual-Cue-Dependent Memory Circuit for Place Navigation.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Qin, Han; Fu, Ling; Hu, Bo; Liao, Xiang; Lu, Jian; He, Wenjing; Liang, Shanshan; Zhang, Kuan; Li, Ruijie; Yao, Jiwei; Yan, Junan; Chen, Hao; Jia, Hongbo; Zott, Benedikt; Konnerth, Arthur; Chen, Xiaowei
Abstract:
The ability to remember and to navigate to safe places is necessary for survival. Place navigation is known to involve medial entorhinal cortex (MEC)-hippocampal connections. However, learning-dependent changes in neuronal activity in the distinct circuits remain unknown. Here, by using optic fiber photometry in freely behaving mice, we discovered the experience-dependent induction of a persistent-task-associated (PTA) activity. This PTA activity critically depends on learned visual cues and bui...     »
Journal title abbreviation:
Neuron
Year:
2018
Journal volume:
99
Journal issue:
1
Pages contribution:
47-55.e4
Fulltext / DOI:
doi:10.1016/j.neuron.2018.05.021
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29909996
Print-ISSN:
0896-6273
TUM Institution:
Institut für Neurowissenschaften
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